LAMC1 Rabbit pAb (一抗) | Bioss

2026-03-02~2026-04-30,KXJ26032026-03-02~2026-04-30,促销赠品
LAMC1 Rabbit pAb (一抗) | Bioss
货号:bs-5122R
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概述

产品编号
bs-5122R
产品类型
农牧业/家禽抗体
英文名称
LAMC1 Rabbit pAb
中文名称
层粘连蛋白γ1抗体
英文别名
LAMB2; LAMC1_HUMAN; LAMC1; Laminin B2 chain; Laminin-1 subunit gamma; Laminin-10 subunit gamma; Laminin-11 subunit gamma; Laminin-2 subunit gamma; Laminin-3 subunit gamma; Laminin-4 subunit gamma; Laminin-6 subunit gamma; Laminin-7 subunit gamma; Laminin-8 subunit gamma; Laminin-9 subunit gamma; S-laminin subunit gamma (S-LAM gamma); Q5VYE7_HUMAN; Q6NVY8_HUMAN; LAMC1_MOUSE; Lamb-2; Lamc-1;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human LAMC1: 1501-1609/1609
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
174 kDa
检测分子量
230 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. The gamma 1 chain, formerly thought to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domains I and II. The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes.
层粘连蛋白γ1抗体-bs-5122R层粘连蛋白γ1抗体-bs-5122R

产品应用

应用已检合格种属预测种属推荐稀释比例
WBRatHuman, Mouse, Cow1:500-2000
IHC-PMouseHuman, Rat, Cow1:100-500
IHC-FMouseHuman, Rat, Cow1:100-500
IFMouseHuman, Rat, Cow1:100-500

交叉反应

交叉反应: Mouse, Rat (predicted: Human, Cow)

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靶标

基因名
LAMC1
蛋白名
Laminin subunit gamma-1
亚基
Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Gamma-1 is a subunit of laminin-1 (laminin-111 or EHS laminin), laminin-2 (laminin-211 or merosin), laminin-3 (laminin-121 or S-laminin), laminin-4 (laminin-221 or S-merosin), laminin-6 (laminin-311 or K-laminin), laminin-7 (laminin-321 or KS-laminin), laminin-8 (laminin-411), laminin-9 (laminin-421), laminin-10 (laminin-511) and laminin-11 (laminin-521).
亚细胞定位
Secreted, extracellular space, extracellular matrix, basement membrane.
组织特异性
Found in the basement membranes.
相似性
Contains 11 laminin EGF-like domains.
Contains 1 laminin IV type A domain.
Contains 1 laminin N-terminal domain.
功能
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

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