CD9蛋白抗体

CD9蛋白抗体
货号:bs-2489R
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概述

产品编号
bs-2489R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
CD9 Rabbit pAb
中文名称
CD9蛋白抗体
英文别名
BTCC-1; DRAP-27; MIC3; MRP-1; TSPAN-29; TSPAN29; CD9_HUMAN; CD9; 5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein (MRP-1); Tetraspanin-29 (Tspan-29); p24; CD9_MOUSE; CD9_RAT;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human CD9: 101-200/228 <Extracellular>
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
24 kDa
检测分子量
24 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
CD9是一种普遍存在于细胞膜表面属于四跨膜超蛋白家族的细胞表面糖蛋白, 参与质膜的融合过程,在细胞膜生物学中发挥重要作用。
近年来经研究发现,CD9与多种肿瘤转移有关,故称肿瘤转移抑制基因亦称抗肿瘤转移基因。是一个新的肿瘤转移抑制基因膜运动相关蛋白-1(CD9/MRP-1),其分子功能还有待于进一步研究。CD9主要在早B细胞、活化T淋巴细胞、嗜酸性粒细胞、嗜碱性粒细胞和血小板表达。
背景资料
This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011]
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产品应用

应用已检合格种属预测种属推荐稀释比例
WBMouse, RatHuman, Rabbit, Pig, Sheep, Cow, Dog1:500-2000
Flow-CytHuman, Mouse, RatRabbit, Pig, Sheep, Cow, Dog1μg/Test

交叉反应

交叉反应: Human, Mouse, Rat (predicted: Rabbit, Pig, Sheep, Cow, Dog)

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靶标

基因名
CD9
蛋白名
CD9 antigen
亚基
Forms both disulfide-linked homodimers and higher homooligomers as well as heterooligomers with other members of the tetraspanin family. Associates with CR2/CD21 and with PTGFRN/CD9P1. Interacts directly with IGSF8.
亚细胞定位
Membrane; Multi-pass membrane protein.
组织特异性
Expressed by a variety of hematopoietic and epithelial cells.
翻译后修饰
Protein exists in three forms with molecular masses between 22 and 27 kDa, and is known to carry covalently linked fatty acids.
相似性
Belongs to the tetraspanin (TM4SF) family.
功能
Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion.

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