NAT10 Rabbit pAb (一抗) | Bioss
货号：bs-7757R
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概述
产品编号
bs-7757R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
NAT10 Rabbit pAb
中文名称
乙酰基转移酶10抗体
英文别名
ALP; Kre33; NET43; NAT10_HUMAN; NAT10; 18S rRNA cytosine acetyltransferase; N-acetyltransferase 10; N-acetyltransferase-like protein (hALP); 2.3.1.-; KIAA1709;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human NAT10: 51-150/1025
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
116 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| IHC-P | Rat | Human, Mouse, Pig, Sheep, Cow, Chicken, Dog, Horse | 1:100-500 |
| IHC-F | Rat | Human, Mouse, Pig, Sheep, Cow, Chicken, Dog, Horse | 1:100-500 |
| IF | Rat | Human, Mouse, Pig, Sheep, Cow, Chicken, Dog, Horse | 1:100-500 |
交叉反应
交叉反应: Rat (predicted: Human, Mouse, Pig, Sheep, Cow, Chicken, Dog, Horse)
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靶标
基因名
NAT10
蛋白名
RNA cytidine acetyltransferase
亚基
Interacts with SUN1 (via N-terminus). Also interacts with TERT.
亚细胞定位
Nucleus, nucleolus. Note=Nucleolar in interphase and redistributes to the perichromosomal layer and to the midbody during telophase.
相似性
Belongs to the UPF0202 family.
Contains 1 N-acetyltransferase domain.
Contains 1 N-acetyltransferase domain.
功能
Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division.
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