PDE3B is found in lymphocytes. The PDE7A1 (HCP1) isozyme and the PDE7A2 proteins, alternate splice products of PDE7A, are highly expressed in skeletal muscle. PDE7B is most highly expressed in pancreas. The PDE family contains proteins that serve tissue-specific roles in regulation of lipolysis, glycogenolysis, myocardial contractility, and smooth muscle relaxation.
基因名
PDE3B
蛋白名
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B
亚细胞定位
Membrane.
组织特异性
Abundant in adipose tissues.
相似性
Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily.
功能
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism.
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
WB
Human
Mouse, Rat, Rabbit, Pig, Dog, Horse
1:500-2000
交叉反应
交叉反应: Human (predicted: Mouse, Rat, Rabbit, Pig, Dog, Horse)