G蛋白偶联受体105抗体

货号:bs-12028R
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概述

产品编号
bs-12028R
英文名称
GPR105 Rabbit pAb
中文名称
G蛋白偶联受体105抗体
英文别名
BPR105; GPR105; P2Y14; P2Y14_HUMAN; P2RY14; G-protein coupled receptor 105; UDP-glucose receptor; KIAA0001;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human G-protein coupled receptor 105: 125-230/338 <Extracellular>
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
39 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
GPR105 is widely expressed throughout many brain regions where it localizes to glial cells, and specifically co-localizes with astrocytes. GPR105 is upregulated when a tissue is immunologically challenged with lipopolysaccharide, leading to the theory that GPR105 may play an important role in modulating peripheral and neuroimmune function.

产品应用

应用已检合格种属预测种属推荐稀释比例
IHC-PHuman, Mouse, Rat1:100-500
IHC-FHuman, Mouse, Rat1:100-500
IFHuman, Mouse, Rat1:100-500
ICC/IFHuman, Mouse, Rat1:100-500
ELISAHuman, Mouse, Rat1:5000-10000

交叉反应

交叉反应: (predicted: Human, Mouse, Rat)

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靶标

基因名
P2RY14
蛋白名
P2Y purinoceptor 14
亚细胞定位
Cell membrane; Multi-pass membrane protein.
组织特异性
Highest expression in the placenta, adipose tissue, stomach and intestine, intermediate levels in the brain, spleen, lung and heart, lowest levels in the kidney.
相似性
Belongs to the G-protein coupled receptor 1 family.
功能
Receptor for UDP-glucose and other UDP-sugar coupled to G-proteins. Not activated by ATP, ADP, UTP or ATP.

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具体参考文献:bs-12028R 被引用于3文献中

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