Arginase 1 Rabbit pAb (一抗) | Bioss

2026-05-01~2026-06-30,AB2605
Arginase 1 Rabbit pAb (一抗) | Bioss
货号:bs-23837R
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概述

产品编号
bs-23837R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
Arginase 1 Rabbit pAb
中文名称
精氨酸酶1抗体
英文别名
AI; Arg-1; PGIF; ARGI1_BOVIN; ARG1; Liver-type arginase; Type I arginase; 3.5.3.1; ARGI1_HUMAN; ARGI1_MOUSE; ARGI1_PIG; ARGI1_RABIT; ARGI1_RAT; arginase 1; arginase, liver; arginase-1
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human Arginase 1
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
35 kDa
检测分子量
35-40 kDa
浓度
1mg/1ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Arginase I which is expressed almost exclusively in the liver, catalyzes the conversion of arginine to ornithine and urea . The human arginase I gene, which maps to chromosome 6q23, encodes a 322 amino acid protein. Arginase I exists as a homotrimeric protein and contains a binuclear manganese cluster. Arginase II catalyzes the same reaction as arginase I, but differs in its tissue specificity and subcellular location. Specifically, arginase II localizes to the mitochondria. Arginase II is expressed in non-hepatic tissues, with the highest levels of expression in the kidneys, but, unlike arginase I, is not expressed in liver. The human arginase II gene, which maps to chromosome 14q24.1-q24.3, encodes a 354 amino acid protein. In addition, arginase II contains a putative amino-terminal mitochondrial localization sequence.
精氨酸酶1抗体-bs-23837R精氨酸酶1抗体-bs-23837R精氨酸酶1抗体-bs-23837R

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman, RatMouse, Rabbit, Pig, Dog1:500-2000
IHC-PRatHuman, Mouse, Rabbit, Pig, Dog1:100-500
IHC-FRatHuman, Mouse, Rabbit, Pig, Dog1:100-500
IFRatHuman, Mouse, Rabbit, Pig, Dog1:100-500

交叉反应

交叉反应: Human, Rat (predicted: Mouse, Rabbit, Pig, Dog)

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靶标

基因名
ARG1
蛋白名
Arginase-1
亚基
Homotrimer.
亚细胞定位
Cytoplasm.
疾病
Defects in ARG1 are the cause of argininemia (ARGIN) ; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia.
相似性
Belongs to the arginase family.

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具体参考文献:bs-23837R 被引用于20文献中

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