猪繁殖与呼吸综合征(Porcine reproductive and respiratory syndrome,PRRS)也称猪蓝耳病,是由动脉炎病毒科动脉炎病毒属的猪繁殖与呼吸综合征病毒,(Porcine reproductive and respiratory syndrome virus,PRRSV)引起的一种严重的病毒性传染病,该病以引起母猪的繁殖障碍、仔猪和育成猪呼吸道症状及高死亡率为主要特征。自1987年首次发现以来,该病广泛流行于世界各主要养猪国家和地区,已成为威胁养猪业的主要疫病之一。2006年以来,由该病毒变异株引起的高致病性猪蓝耳病(Highlypathogenicporcinereproductiveandrespiratorysyndrome,HPPRRS)在我国广泛流行给养猪业带来了巨大的损失。
背景资料
PRRSV is a small, enveloped RNA virus. It contains a single-stranded, positive-sense, RNA genome with a size of approximately 15 kilobases. The genome contains nine open reading frames. PRRSV is a member of the genus Arterivirus, family Arteriviridae, order Nidovirales. Subclinical infections are common, with clinical signs occurring sporadically in a herd. Clinical signs include reproductive failure in sows such as abortions and giving birth to stillborn or mummified fetuses, and cyanosis of the ear and vulva. In neonatal pigs, the disease causes respiratory distress, with increased susceptibility to respiratory infections such as Glasser's disease.