Periostin Rabbit pAb (一抗) | Bioss

bs-4994R

农牧业/家禽抗体

Periostin Rabbit pAb

成骨细胞特异性因子2抗体

OSF-2; OSF2; PDLPOSTN; PN; A630052E07Rik; PLF; POSTN_HUMAN; POSTN; Osteoblast-specific factor 2 (OSF-2); POSTN_MOUSE;

Rabbit

KLH conjugated synthetic peptide derived from human Periostin.: 21-120/836

IgG

Liquid

affinity purified by Protein A

Polyclonal

100 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

成骨细胞特异性转录因子。

Periostin is a disulfide linked 90 kDa, 811 amino acid protein originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta 1(TGF beta 1) and bone morphogenetic protein (BMP2). Periostin has a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain and a C-terminal domain. The fourfold repeated domain of OSF2 shows homology with the insect protein fasciclin. Periostin mRNA is expressed in the developing mouse embryonic and fetal heart, and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart. Abnormal expression of periostin is also linked to angiogenesis and metastatsis in epithelial tumors.