Recombinant Mouse ST14 Protein, N-His (重组蛋白) | Bioss

bs-106033P

Recombinant Mouse ST14 Protein, N-His

Prss14; Suppressor of tumorigenicity 14 protein homolog; St14; Serine protease 14; Epithin

Lyophilized

AC

28.7 kDa

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

213-449/855

Mouse

N-His

>90% as determined by SDS-PAGE.

E.coli

Reconstitute in sterile water for a stock solution.

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

MTSP1 is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.