Recombinant Human SERPINB3 Protein, N-His

bs-101206P

Recombinant Human SERPINB3 Protein, N-His

Serpin B3; SCCA; Protein T4-A; SERPINB3; SCCA1; Squamous cell carcinoma antigen 1; SCCA-1

Lyophilized

AC

26.62 kDa

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Not tested

1-210/390

Human

N-His

>90% as determined by SDS-PAGE.

E.coli

Reconstitute in sterile water for a stock solution.

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma.