结缔组织生长因子抗体

结缔组织生长因子抗体
货号:bs-0743R
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概述

产品编号
bs-0743R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
CTGF Rabbit pAb
中文名称
结缔组织生长因子抗体
英文别名
CTGF; HCS24; IBP-8; IGFBP8; KMD; NOV2; SEMDLSL; CTGRP; CCN2_HUMAN; CCN2; Cellular communication network factor 2; Connective tissue growth factor; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8 (IBP-8 | IGF-binding protein 8 | IGFBP-8); CCN2_MOUSE; Protein FISP-12; betaIG-M2; Fisp-12; Fisp12; CCN2_RAT; Connective tissue growth-related protein;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from mouse CTGF: 221-349/349
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
36 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
生长因子和激素( Growth Factor and Hormones)
结缔组织生长因子(CTGF)是调节细胞增生、分化和细胞外基质形成的重要效应分子,可调节机体有关组织、细胞生长并与纤维化发生密切相关的一种因子,因而在肌体的各类创伤修复过程中具有重要的生理学意义
背景资料
The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009].
结缔组织生长因子抗体

产品应用

应用已检合格种属预测种属推荐稀释比例
WBMouseHuman, Rat, Rabbit, Pig, Chicken, Dog1:500-2000

交叉反应

交叉反应: Mouse, Rat (predicted: Human, Rabbit, Pig, Chicken, Dog)

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靶标

基因名
CCN2
蛋白名
CCN family member 2
亚基
Monomer.
亚细胞定位
Secreted, extracellular space, extracellular matrix. Secreted.
组织特异性
Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.
相似性
Belongs to the CCN family.
Contains 1 CTCK (C-terminal cystine knot-like) domain.
Contains 1 IGFBP N-terminal domain.
Contains 1 TSP type-1 domain.
Contains 1 VWFC domain.
功能
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.

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具体参考文献:bs-0743R 被引用于22文献中

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