重组猪圆环病毒CAP蛋白

bs-41401P

Recombinant PCV2 Cap protein, Trx & His

重组猪圆环病毒CAP蛋白

PCV2 ORF2; PCV-2; PCV 2; PCV2; Porcine circovirus 2; Porcine circovirus2; Porcine circovirus-2; Porcine circovirus 2 capsid protein; Porcine circovirus 2; CAPSD_PCV2. ;Recombinant PCV2 Cap protein, Trx & His

Lyophilized or Liquid

AC

41.5

45 kDa

＞0.5 mg/ml

20mM Tris-HCl (pH8.0).

Not tested

1-233/233

Trx & His

>95% as determined by SDS-PAGE

Not analyzed

E.coli

Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

猪圆环病毒-PCV-2是一种嗜单核-巨噬细胞性的病毒，属于圆环病毒科圆环病毒属的成员，根据抗原性及基因组成，分为PCVl和PCV2两种，其中PCV2对猪具有致病性，PCV2(病毒囊膜衣壳蛋白(Cap))主要侵害免疫系统，导致感染猪免疫抑制，降低机体对其他病原体的抵抗力和疫苗的反应性，容易导致其他病毒和细菌的继发感染，使死亡率明显升高。

Self-assembles to form the virion icosahedral capsid with a T=1 symmetry. This very small capsid (17 - 22 nm in diameter) allows the virus to be very stable in the environment and resistant to some disinfectants, including detergents. Essential for the initial attachment to heparan sulfate moities and chondroitin sulfate B of the host cell surface proteoglycans. After attachment, the virus is internalized in a clathrin-, caveolae- and dynamin-independent, actin and Rho-GTPase-mediated pathway and traffics to the nucleus. The capsid protein binds and transports the viral genome and Rep across the nuclear envelope.