PENK Rabbit pAb (一抗) | Bioss

2026-05-01~2026-06-30,AB2605
PENK Rabbit pAb (一抗) | Bioss
货号:bs-1759R
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概述

产品编号
bs-1759R
英文名称
PENK Rabbit pAb
中文名称
甲硫氨酸脑啡肽抗体
英文别名
PE; PENK-A; ENK; PPA; Penk1; Penk-rs; Penk2; PENK_HUMAN; PENK; PENK_MOUSE; PENK_RAT; proenkephalin; preproenkephalin
抗体来源
Rabbit
免疫原
KLH conjugated Met Enkephalin peptide (Tyr-Gly-Gly-Phe-Met)
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
0.5 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the pentapeptide opioids Met-enkephalin and Leu-enkephalin, which are stored in synaptic vesicles, then released into the synapse where they bind to mu- and delta-opioid receptors to modulate the perception of pain. Other non-opioid cleavage products may function in distinct biological activities. [provided by RefSeq, Jul 2015]
甲硫氨酸脑啡肽抗体-bs-1759R

产品应用

应用已检合格种属预测种属推荐稀释比例
Flow-CytHumanMouse, Rat2ug/Test

交叉反应

交叉反应: Human (predicted: Mouse, Rat)

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靶标

基因名
PENK
蛋白名
Proenkephalin-A
亚细胞定位
Secreted.
翻译后修饰
The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing.
相似性
Belongs to the opioid neuropeptide precursor family.
功能
Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(237-258) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum.

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具体参考文献:bs-1759R 被引用于2文献中

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