XIAP Mouse mAb (一抗) - WB | Bioss

bsm-51607M

KO/KD Validated

XIAP Mouse mAb

X-连锁凋亡蛋白/性连锁凋亡抑制蛋白单克隆抗体

API3; BIRC4; IAP-3; ILP1; MIHA; XLP2; hIAP-3; hIAP3; XIAP_HUMAN; XIAP; Baculoviral IAP repeat-containing protein 4; IAP-like protein (ILP | hILP); Inhibitor of apoptosis protein 3 (IAP-3 | hIAP-3 | hIAP3); RING-type E3 ubiquitin transferase XIAP; X-linked inhibitor of apoptosis protein (X-linked IAP); 2.3.2.27; IAP3;

Mouse

Recombinant human XIAP

IgG1, k

Liquid

affinity purified by Protein G

Monoclonal

D1G6

55 kDa

55 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]