phospho-TPH2 (Ser19) Rabbit pAb (一抗) | Bioss

bs-17166R

磷酸化抗体、宠物抗体、农牧业/家禽抗体

phospho-TPH2 (Ser19) Rabbit pAb

磷酸化神经色氨酸羟化酶2抗体

TPH2 (phospho-S19); p-TPH2; phospho-TPH2; TPH2 (phospho-Ser19); ADHD7; NTPH; T23O_BOVIN; TDO2; TDO; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase (TO | TRPO); Tryptophan pyrrolase; Tryptophanase; 1.13.11.11; TPH2_HUMAN; TPH2; Neuronal tryptophan hydroxylase; Tryptophan 5-monooxygenase 2; 1.14.16.4; TPH2_MOUSE; TPH2_RAT;

Rabbit

KLH conjugated synthesised phosphopeptide derived from human TPH2 around the phosphorylation site of Ser19: GF(p-S)LD

IgG

Liquid

affinity purified by Protein A

Polyclonal

56 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Phenylalanine hydroxylase (PAH), tyrosine hydroxylase (TH), tryptophan hydroxylase (TPH) and tryptophan hydroxylase 2 (TPH2) comprise a small family of monooxygenases that catalyze the rate-limiting step in the catabolism of aromatic L-amino acids and utilize tetrahydropterine as a cofactor. TPH2 is highly expressed in the central nervous system (CNS), mainly in the brain. TPH2 catalyzes the first step in the biosynthesis of serotonin in the CNS and melatonin in the pineal gland, and may be involved in the pathology of several neuropsychiatric disorders. Glucocorticoid-mediated reduction of TPH2 is associated with the etiology of mood disorders, specifically psychotic major depression, and TPH2 may be related to dysregulation of serotonin neurotransmission in the brain which commonly leads to suicidal behavior.