血红素氧合酶 1/热休克蛋白32抗体

血红素氧合酶 1/热休克蛋白32抗体
货号:bs-2075R
产品详情
相关标记
相关产品
相关文献
常见问题

概述

产品编号
bs-2075R
产品类型
衰老相关抗体、宠物抗体、农牧业/家禽抗体
英文名称
Heme Oxygenase 1 Rabbit pAb
中文名称
血红素氧合酶 1/热休克蛋白32抗体
英文别名
HO-1; Hsp32; HMOX1D; bK286B10; D8Wsu38e; HO1; Hemox; Hmox; HEOXG; Heox; HMOX1_BOVIN; HMOX1; 1.14.14.18; HMOX1_HUMAN; HO; HMOX1_MOUSE; P32 protein;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human HO-1: 101-200/288
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
32 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
血红素氧合酶-1又称HSP-32( Heat Shock Protein 32)是一种血红素降解的催化酶,在NADPH 和细胞色素P-450还原酶及分子氧作用下,HO-1催化血红素降解为胆绿素、CO和铁,前者还原成胆红素后具有很强的抗氧化能力,后者是一种重要的信使分子。
近年研究发现,热休克蛋白32(HO-1)及其酶解产物胆红素、CO、转铁蛋白共同发挥着抗炎、抗氧化、抑制细胞凋亡和改善组织微循环等作用,广泛参与心、脑、肺、肝、肾等组织细胞的抗氧化应激损伤,是机体最重要的内源性保护体系之一,尤其是其组织器官的保护作用已逐渐成为目前研究的一个热点。
背景资料
The hemeoxygenase-1 calls that the hemoglobin oxidizes to synthesize the enzyme again-1( hemeoxygenase-1, HO-1) is the catalyst enzyme that a kind of hemoglobin declines the solution, under the NADPH and the cell dye P-450 revivification enzymes and the member oxygen functions, the catalyst HO-1 hemoglobin declines the solution as the courage green vegetable, CO and irons, the former revivification has the very strong anti- to oxidize the ability after become the red vegetable of courage , the latter is a kind of important letter to make the member.
血红素氧合酶 1/热休克蛋白32抗体血红素氧合酶 1/热休克蛋白32抗体

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman, RatMouse, Rabbit, Pig, Sheep, Cow, Chicken, Dog, GuineaPig, Horse1:500-2000
IHC-PRatHuman, Mouse, Rabbit, Pig, Sheep, Cow, Chicken, Dog, GuineaPig, Horse1:100-500
IHC-FRatHuman, Mouse, Rabbit, Pig, Sheep, Cow, Chicken, Dog, GuineaPig, Horse1:100-500
IFRatHuman, Mouse, Rabbit, Pig, Sheep, Cow, Chicken, Dog, GuineaPig, Horse1:100-500

交叉反应

交叉反应: Human, Rat (predicted: Mouse, Rabbit, Pig, Sheep, Cow, Chicken, Dog, GuineaPig, Horse)

相关产品

暂无相关产品

靶标

基因名
HMOX1
蛋白名
Heme oxygenase 1
亚细胞定位
Microsome. Endoplasmic reticulum.
组织特异性
Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level).
疾病
Defects in HMOX1 are the cause of heme oxygenase 1 deficiency (HMOX1D) [MIM:614034]. A disease characterized by impaired stress hematopoiesis, resulting in marked erythrocyte fragmentation and intravascular hemolysis, coagulation abnormalities, endothelial damage, and iron deposition in renal and hepatic tissues. Clinical features include persistent hemolytic anemia, asplenia, nephritis, generalized erythematous rash, growth retardation and hepatomegaly.
相似性
Belongs to the heme oxygenase family.
功能
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed.

标记抗体

暂无标记数据

同靶标产品

暂无同靶标产品

相关文献

提示: 发表研究结果有使用 bs-2075R 时请让我们知道,以便我们可以引用参考文章。作为回馈,资料提供者将获得我们送上的小礼品。
具体参考文献:bs-2075R 被引用于69文献中

暂无相关文献

常见问题

暂无常见问题