Ifnlr1 | IL-28RA Rabbit pAb (一抗) | Bioss

bs-20896R

Ifnlr1 | IL-28RA Rabbit pAb

白细胞介素28受体α抗体

CRF2/12; IFNLR; IL-28R1; IL28RA; LICR2; CRF2-12; RGD1562689; INLR1_HUMAN; IFNLR1; IFN-lambda receptor 1; IFN-lambda-R1; Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12 (CRF2-12); Interleukin-28 receptor subunit alpha (IL-28 receptor subunit alpha | IL-28R-alpha | IL-28RA); Likely interleukin or cytokine receptor 2 (LICR2); INLR1_MOUSE; IFN-lambda R1; interferon lambda receptor 1; interleukin 28 receptor, alpha; interleukin 28 receptor, alpha (interferon, lambda receptor); interferon, lambda receptor 1

Rabbit

KLH conjugated synthetic peptide derived from mouse IL28 Receptor alpha: 21-120/520

IgG

Liquid

affinity purified by Protein A

Polyclonal

56 kDa

52 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Ifnlr1

Interferon lambda receptor 1

Heterodimer with IL10RB.

Membrane; Single-pass type I membrane protein

Widely expressed.

Belongs to the type II cytokine receptor family.
Contains 1 fibronectin type-III domain.

IL28RA is a class II cytokine receptor that interacts with IL10RB to bind IL28A, IL28B, and IL29, which are related to type I interferons. These ligands play a critical role in response to microbial challenge and activate the JAK/STAT signaling system. It heterodimers with IL10RB. There are 4 isoforms as result of alternative splicing. It is widely expressed. IL28RA belongs to the type II cytokine receptor family, and contains 1 fibronectin type III domain.