S100A1 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss

Rrmab?兔单抗
2026-05-01~2026-06-30,AB2605
S100A1 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss
货号:bsm-63044R
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概述

产品编号
bsm-63044R
产品类型
重组兔单抗、mIHC精品抗体
英文名称
S100A1 Recombinant Rabbit mAb
中文名称
S100A1重组兔单抗
英文别名
S100; S100-alpha; S100A; S10A1_HUMAN; S100A1; S-100 protein alpha chain; S-100 protein subunit alpha; S100 calcium-binding protein A1; S10A1_MOUSE; S10A1_RAT; S100 calcium binding protein A1
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human S100A1: 1-94
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
13F15
理论分子量
11 kDa
检测分子量
10 kDa
储存液
10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
星型胶质细胞标志物
S100A1是钙结合蛋白家族S100亚家族中一个小分子量的酸性蛋白,对稳定蛋白质分子的构象起到一定的作用。
背景资料
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008]
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产品应用

应用已检合格种属预测种属推荐稀释比例
WBMouseHuman1:500-2000
IHC-PHuman, Mouse1:100-500
IHC-FHuman, Mouse1:100-500
IFHuman, Mouse1:100-500

交叉反应

交叉反应: Human, Mouse

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靶标

基因名
S100A1
蛋白名
Protein S100-A1
亚基
Dimer of either two alpha chains, or two beta chains, or one alpha and one beta chain. Also forms heterodimers with S100P. Interacts with AGER and CAPZA1. Interacts with FKBP4. Interacts with RYR1 and RYR2. Interacts with CACYBP in a calcium-dependent manner. Interacts with PPP5C (via TPR repeats); the interaction is calcium-dependent and modulates PPP5C activity.
亚细胞定位
Cytoplasm.
组织特异性
Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain.
相似性
Belongs to the S-100 family.
Contains 2 EF-hand domains.
功能
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.

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