Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues (Probable). Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane.
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
WB
Human
1:500-2000
IHC-P
Human
1:100-500
IHC-F
Human
1:100-500
IF
Human
1:100-500
Flow-Cyt
Human
1:50-100
ICC/IF
Human
1:50-200
交叉反应
交叉反应: Human
相关产品
暂无相关产品
靶标
基因名
RBP4
蛋白名
Retinol-binding protein 4
亚细胞定位
Secreted.
疾病
Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.
相似性
Belongs to the calycin superfamily. Lipocalin family.
功能
Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.