Dopamine Transporter Recombinant Rabbit mAb (一抗) - WB,Flow-Cyt,IP | Bioss

Name: 多巴胺转运蛋白DAT重组兔单抗（Dopamine Transporter Recombinant Rabbit mAb）
Brand: 北京博奥森生物科技有限公司
SKU: bsm-61434R
Availability: InStock

Rrmab^?兔单抗

2026-05-01~2026-06-30，AB2605

一键复制说明书

货号：bsm-61434R

产品详情

概述

产品编号

bsm-61434R

产品类型

重组兔单抗

英文名称

Dopamine Transporter Recombinant Rabbit mAb

中文名称

多巴胺转运蛋白DAT重组兔单抗

英文别名

DAT; DAT1; PKDYS; PKDYS1; SC6A3_HUMAN; SLC6A3; DA transporter; Solute carrier family 6 member 3; SC6A3_MOUSE; SC6A3_RAT; solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; dopamine transporter 1; solute carrier family 6 (neurotransmitter transporter), member 3; dopamine transporter; Sodium-dependent dopamine transporter

抗体来源

Rabbit

免疫原

A synthesized peptide derived from human Dopamine transporter: 150-215/620

亚型

IgG

性状

Liquid

纯化方法

affinity purified by Protein A

克隆类型

Recombinant

理论分子量

68 kDa

检测分子量

50 kDa

储存液

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

研究领域

Neuroscience > Neurotransmitter > Biogenic Amines > Dopamine

Neuroscience > Neurotransmitter > Transporters > Dopamine

SWISS

Q01959

Gene ID

6531

保存条件

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

注意事项

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

数据库链接

Entrez Gene : 6531 Human

Entrez Gene : 13162 Mouse

Entrez Gene : 24898 Rat

Omim : 126455 Human

SwissProt : Q01959 Human

SwissProt : Q61327 Mouse

SwissProt : P23977 Rat

Unigene : 406 Human

Unigene : 41993 Mouse

Unigene : 10093 Rat

产品介绍

DATI 可能参与神经系统的多种活动，如学习记忆、嗅觉、感觉、运动、多巴胺神经递质活动的调节，而且可能参与胶质瘤等神经系统肿瘤的发生,阳性着色主要定位于细胞质，但也可见到有些细胞核内的阳性染色.

背景资料

Mediates sodium- and chloride-dependent transport of dopamine.Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline).Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling.

产品应用

应用	预测种属	推荐稀释比例
WB	Human	1:500-2000
Flow-Cyt	Human	1:50-100
IP	Human	1:20-50

交叉反应

交叉反应: Human

靶标

基因名

SLC6A3

蛋白名

Sodium-dependent dopamine transporter

亚基

Homooligomer; disulfide-linked. Interacts with PRKCABP and TGFB1I1. Interacts (via N-terminus) with SYNGR3 (via N-terminus). Interacts with SLC18A2.

亚细胞定位

Membrane; Multi-pass membrane protein.

疾病

Defects in SLC6A3 are the cause of dystonia-parkinsonism infantile (DYTPRI) [MIM:613135]. It is a neurodegenerative disorder characterized by infantile onset of parkinsonism and dystonia. Other neurologic features include global developmental delay, bradikinesia and pyramidal tract signs.

相似性

Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.

功能

Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.

Dopamine Transporter Recombinant Rabbit mAb (一抗) - WB,Flow-Cyt,IP | Bioss

概述

产品应用

交叉反应

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靶标

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