RREB1 Rabbit pAb (一抗) | Bioss
货号：bs-18856R
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概述
产品编号
bs-18856R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
RREB1 Rabbit pAb
中文名称
RREB1蛋白抗体
英文别名
FINB; HNT; LZ321; RREB-1; Zep-1; 1110037N09Rik; B930013M22Rik; sao; RREB1_HUMAN; RREB1; Finger protein in nuclear bodies; Raf-responsive zinc finger protein LZ321; Zinc finger motif enhancer-binding protein 1 (Zep-1); RREB1_MOUSE; RAS-responsive zinc finger transcription factor RREB;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human RREB1: 1-100/1687
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
181 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > Nuclear Receptors > Testosterone
Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger
Epigenetics and Nuclear Signaling > Transcription > Polymerase associated factors > Pol II Transcription
Epigenetics and Nuclear Signaling > Transcription > Transcription Factors
Signal Transduction > Signaling Pathway > Nuclear Signaling > Nuclear Hormone Receptors > Testosterone
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| IHC-P | Mouse | Human, Rat, Rabbit, Sheep, Cow, Chicken, Dog, Horse | 1:100-500 |
| IHC-F | Mouse | Human, Rat, Rabbit, Sheep, Cow, Chicken, Dog, Horse | 1:100-500 |
| IF | Mouse | Human, Rat, Rabbit, Sheep, Cow, Chicken, Dog, Horse | 1:100-500 |
交叉反应
交叉反应: Mouse (predicted: Human, Rat, Rabbit, Sheep, Cow, Chicken, Dog, Horse)
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暂无相关产品
靶标
基因名
RREB1
蛋白名
Ras-responsive element-binding protein 1
亚细胞定位
Nucleus speckle.
组织特异性
Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain.
翻译后修饰
Phosphorylated upon DNA damage, probably by ATM or ATR.
相似性
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 15 C2H2-type zinc fingers.
Contains 15 C2H2-type zinc fingers.
功能
Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1.
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