KCTD1 (potassium channel tetramerisation domain containing 1), also known as C18orf5, is a 257 amino acid protein that contains one BTB domain, suggesting an involvement in transcriptional control. The gene encoding KCTD1 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
WB
Mouse
Human, Rat, Rabbit
1:500-2000
交叉反应
交叉反应: Mouse (predicted: Human, Rat, Rabbit)
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暂无相关产品
靶标
基因名
KCTD1
蛋白名
BTB/POZ domain-containing protein KCTD1
亚细胞定位
Nucleus.
组织特异性
Expressed in mammary gland, kidney, brain and ovary.
翻译后修饰
Sumoylated.
相似性
Contains 1 BTB (POZ) domain.
功能
May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent.