PE标记的小鼠CD206单克隆抗体

货号:bsm-30276A-PE
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概述

产品编号
bsm-30276A-PE
产品类型
流式抗体
英文名称
mouse CD206 Rat mAb, PE conjugated
中文名称
PE标记的小鼠CD206单克隆抗体
英文别名
Mannose Receptor; C-type lectin domain family 13 member D; CD 206; CD206; CD206 antigen; CLEC13D; CLEC13DL; Macrophage mannose receptor; Mannose receptor C type 1; MMR; MRC 1; MRC-1; MRC1_MOUSE; Macrophage mannose receptor 1; MRC1L1; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1.
标记
PE
Excitation spectrum: 496/564nm
Emission spectrum: 578nm
抗体来源
Rat
亚型
Rat IgG2a, k
纯化方法
affinity purified by Protein G
克隆类型
Monoclonal
克隆号
6G9
储存液
0.01M PBS (pH7.4), 0.5% BSA, 0.02% Proclin300.
保存条件
Store at 2-8℃. Protect from light. Avoid freezing.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
巨噬细胞甘露糖受体,主要存在于巨噬细胞膜表面的模式识别受体,能够特异性识别甘露糖、岩藻糖或N-乙酰葡糖胺,介导巨噬细胞吞噬抗原,启动免疫反应.
背景资料
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. This gene is in close proximity to MRC1L1. The gene loci including this gene, MRC1L1, as well as LOC340843 and LOC340893, consist of two nearly identical, tandemly linked genomic regions, which are thought to be a part of a duplicated region. [provided by RefSeq].

交叉反应

交叉反应: (predicted: Mouse)

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靶标

基因名
MRC1
蛋白名
Macrophage mannose receptor 1
亚细胞定位
Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein.
相似性
Contains 8 C-type lectin domains.
Contains 1 fibronectin type-II domain.
[SIMILARITY] Contains 1 ricin B-type lectin domain.
功能
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.

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