Human sST2 Mouse mAb (IVD抗体) | Bioss

货号:V3705
产品详情
相关标记
相关产品
相关文献
常见问题

概述

产品编号
V3705
英文名称
Human sST2 Mouse mAb
中文名称
人生长抑素受体2单克隆抗体
英文别名
somatostatin receptor 2; Somatostatin receptor type 2; SRIF1; SS2R; SST2; SSTR2; SRIF-1; SS-2-R; SS2-R; SSR2_HUMAN.
抗体来源
Mouse
免疫原
Recombinant Human sST2 Protein: 19-328/556
亚型
IgG2b
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Monoclonal
克隆号
5H4
理论分子量
41 kDa
储存液
PBS (pH7.4).
SWISS
Gene ID
纯度
>90% as determined by SDS-PAGE
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
SSTR2的表达在肿瘤的分布、发生和发展中起重要作用。目前主要用于肿瘤方面的研究。
背景资料
Somatostatin is a tetradecapeptide that is widely distributed in the body and is one of five receptor subtypes termed SSTr1-. These receptors function in the regulation of numerous phsiological processes such as the secretion of insulin, glucagon and growth hormone as wel as cell growth induced by neuronal excitation in both the central and peripheral nervous systems. Somatostatin receptos are activated via sonatostatin secreted by nerve and endocrine cells. Somatostatin Receptor 2 (SSR2), along with SSR1, is expressed at the highest levels in the stomach and jejunum, cerebrum and kidney, respectively.

产品应用

产品应用: ELISA=1:5000-10000, ICA

交叉反应

交叉反应: Human

相关产品

暂无相关产品

靶标

基因名
SSTR2
蛋白名
Somatostatin receptor type 2
亚基
The C-terminus interacts with SHANK1 PDZ domain.
亚细胞定位
Cell membrane; Multi-pass membrane protein.
组织特异性
Cerebrum and kidney. In lesser amounts in jejunum, colon and liver.
相似性
Belongs to the G-protein coupled receptor 1 family.
功能
Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels.

同靶标产品

相关文献

常见问题