β3肾上腺素能受体抗体

bs-1063R

宠物抗体、农牧业/家禽抗体

ADRB3 Rabbit pAb

β3肾上腺素能受体抗体

BETA3AR; Adrb-3; beta 3-AR; ADRB; ADRB3_HUMAN; ADRB3; Beta-3 adrenoreceptor (Beta-3 adrenoceptor); ADRB3R; B3AR; ADRB3_MOUSE; B3bar; ADRB3_RAT;

Rabbit

KLH conjugated synthetic peptide derived from human ADRB3: 310-408/408 <Cytoplasmic>

IgG

Liquid

affinity purified by Protein A

Polyclonal

44 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

ARβ3是新近发现的,继β1和β2之后的第3个β型肾上腺素受体亚型.分子量：44KDa(404AA)
近年来研究表明:β3-肾上腺素受体该受体基因突变或基因多态性与机体肥胖及心血管疾病相关;心力衰竭时该受体的含量明显增加,β3肾上腺素能受体与心血管疾病的相关研究可能为心血管疾病的预测、防治的新方法.

beta 3 Adrenergic Receptor is located mainly in adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Beta adrenergic receptors are involved in the epenephrine and norepinephrine-induced activation of adenylate cyclase through the action of G proteins. beta 3 Adrenergic Receptor expression has been documented in adipose tissues, heart, and in smooth muscle of digestive and urinary tract organs (bladder, colon, small intestine, stomach, ureter). Utilization of alternate promoters and/or 3-prime untranslated regions may result in tissue-specific regulation of the expression of this protein.