KCNJ6 Recombinant Rabbit mAb (一抗) | Bioss
Rrmab?兔单抗
货号：bsm-60755R
产品详情
相关标记
相关产品
相关文献
常见问题
概述
产品编号
bsm-60755R
产品类型
重组兔单抗
英文名称
KCNJ6 Recombinant Rabbit mAb
中文名称
G蛋白激活内流钾通道蛋白2重组兔单克隆抗体
英文别名
BIR1; GIRK-2; GIRK2; KATP-2; KATP2; KCNJ7; KIR3.2; KPLBS; hiGIRK2; weaver; wv; KCNJ6_HUMAN; KCNJ6; Inward rectifier K(+) channel Kir3.2; Potassium channel, inwardly rectifying subfamily J member 6; KCNJ6_MOUSE; W; KCNJ6_RAT; potassium inwardly rectifying channel subfamily J member 6; potassium inwardly-rectifying channel, subfamily J, member 6; G protein-activated inward rectifier potassium channel 2
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from mouse KCNJ6
亚型
IgG
性状
Lyophilized or Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
理论分子量
47 kDa
检测分子量
40, 48 kDa
浓度
1mg/ml
储存液
PBS, Glycerol, BSA.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Mouse | 1:500-2000 |
交叉反应
交叉反应: Mouse
相关产品
暂无相关产品
靶标
基因名
KCNJ6
蛋白名
G protein-activated inward rectifier potassium channel 2
亚基
Associates with GIRK1 or GIRK4 to form a G-protein-activated heteromultimer pore-forming unit. The resulting inward current is much larger.
亚细胞定位
Membrane; Multi-pass membrane protein.
组织特异性
Most abundant in cerebellum, and to a lesser degree in islets and exocrine pancreas.
相似性
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.
功能
This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
同靶标产品
相关文献
提示: 发表研究结果有使用 bsm-60755R 时请让我们知道，以便我们可以引用参考文章。作为回馈，资料提供者将获得我们送上的小礼品。