Percp-Cy5.5标记小鼠CD3e单克隆抗体

bsm-30151H-PerCP-Cy5.5

流式抗体

Mouse CD3e Hamster mAb, Percp-Cy5.5 conjugated

Percp-Cy5.5标记小鼠CD3e单克隆抗体

CD3 epsilon; CD3e; CD3e antigen epsilon polypeptide(TiT3 complex); CD3E antigen epsilon polypeptide; CD3E antigen, epsilon subunit; CD3e molecule epsilon; CD3e molecule, epsilon(CD3 TCR complex); CD3e molecule, epsilon(CD3-TCR complex); CD3E_MOUSE; IMD18; T cell antigen receptor complex epsilon subunit of T3; T cell surface antigen T3/Leu 4 epsilon chain; T cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE.

PerCP-Cy5.5
Excitation spectrum: 482nm
Emission spectrum: 694nm

Hamster

Liquid

affinity purified by Protein G

Monoclonal

3G4

20 kDa

20 kDa

0.01M PBS (pH7.4), 0.5% BSA, 0.02% Proclin300.

Store at 2-8℃. Protect from light. Avoid freezing.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD3 epsilon 参与T淋巴细胞介导,主要用于免疫排斥方面的研究.

CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.