TIMP-3 Rabbit pAb (一抗) | Bioss

bs-0417R

农牧业/家禽抗体

TIMP-3 Rabbit pAb

金属蛋白酶组织抑制因子-3抗体

HSMRK222; K222; K222TA2; SFD; Timp-3; TIMP3_HUMAN; TIMP3; Protein MIG-5; Tissue inhibitor of metalloproteinases 3 (TIMP-3); TIMP3_MOUSE; Sun; TIMP3_RAT; TIMP metallopeptidase inhibitor 3; tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory)

Rabbit

KLH conjugated synthetic peptide derived from human TIMP-3: 151-211/211

IgG

Liquid

affinity purified by Protein A

Polyclonal

21 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

合成与降解（Synthesis and Degradation） 近年来，国内外科研人员对TIMP-3的抗肿瘤作用日益被重视，学者认为：TIMP-3具有强烈促凋亡、抑制血管生成、抗肿瘤浸润作用，TIMP-3与TIMP-1、2且相互间有明显协同抗肿瘤作用

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008].