May regulate IL2 production by T-cells. May be involved in neuron regeneration.
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
WB
Mouse
Human, Rat, Sheep, Chicken, Horse
1:500-2000
交叉反应
交叉反应: Mouse (predicted: Human, Rat, Sheep, Chicken, Horse)
相关产品
暂无相关产品
靶标
基因名
NAV3
蛋白名
Neuron navigator 3
亚细胞定位
Nucleus outer membrane.
组织特异性
Highly expressed in brain. Expressed at low levels in heart and placenta. Present in activated T-cells but not in resting T-cells (at protein level). Down-regulated in primary neuroblastoma.
疾病
Note=A chromosomal aberration disrupting NAV3 has been found in patients with Sezary syndrome. Translocation t(12;18)(q21;q21.2).
相似性
Sequence similarities; Belongs to the Nav/unc-53 family.
Contains 1 CH (calponin-homology) domain.
功能
May regulate IL2 production by T-cells. May be involved in neuron regeneration.