ENO1 Rabbit pAb (一抗) | Bioss

2026-03-02~2026-04-30,KXJ26032026-03-02~2026-04-30,促销赠品
ENO1 Rabbit pAb (一抗) | Bioss
货号:bs-3978R
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概述

产品编号
bs-3978R
产品类型
农牧业/家禽抗体
英文名称
ENO1 Rabbit pAb
中文名称
MYC启动子结合蛋白1抗体
英文别名
ENO1-IT1; ENO1L1; HEL-S-17; MPB1; NNE; PPH; HEL-S-279; NSE; GSD13; MSE; Eno-1; MBP-1; D6Ertd375e; Eno-2; Eno-3; RNEN3; BBE; ENOA_HUMAN; ENO1; 2-phospho-D-glycerate hydro-lyase; C-myc promoter-binding protein; Enolase 1; MPB-1; Non-neural enolase (NNE); Phosphopyruvate hydratase; Plasminogen-binding protein; 4.2.1.11; MBPB1; ENOG_HUMAN; ENO2; Enolase 2; Neural enolase; Neuron-specific enolase (NSE); ENOB_HUMAN; ENO3; Enolase 3; Muscle-specific enolase (MSE); Skeletal muscle enolase; ENOA_MOUSE; ENOG_MOUSE; ENOB_MOUSE; ENOA_RAT; ENOG_RAT; ENOB_RAT;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human ENO1: 51-150/434
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
47 kDa
检测分子量
47 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011].
背景资料
Enolase 1 is a multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.
Enolase 2 has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.
Enolase 3 appears to have a function in striated muscle development and regeneration.
MYC启动子结合蛋白1抗体-bs-3978RMYC启动子结合蛋白1抗体-bs-3978R

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman, Mouse, RatRabbit, Cow1:500-2000
IHC-PHuman, Mouse, Rat, Rabbit, Cow1:100-500
IHC-FHuman, Mouse, Rat, Rabbit, Cow1:100-500
IFRatHuman, Mouse, Rabbit, Cow1:100-500

交叉反应

交叉反应: Human, Mouse, Rat (predicted: Rabbit, Cow)

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靶标

基因名
ENO1
蛋白名
alpha-enolase
亚基
Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific. ENO1 interacts with PLG in the neuronal plasma membrane and promotes its activation. The C-terminal lysine is required for this binding.
亚细胞定位
Cytoplasm. Cell membrane. Cytoplasm, myofibril, sarcomere, M line. Isoform MBP-1: Nucleus.
组织特异性
The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
相似性
Belongs to the enolase family.
功能
Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.

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