LMX1B Rabbit pAb (一抗) | Bioss

2026-05-01~2026-06-30,AB2605
LMX1B Rabbit pAb (一抗) | Bioss
货号:bs-11780R
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概述

产品编号
bs-11780R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
LMX1B Rabbit pAb
中文名称
指甲髌骨综合征相关蛋白NPS1抗体
英文别名
FSGS10; LMX1.2; NPS1; Icst; LMX1.1; LMX1B_HUMAN; LMX1B; LIM/homeobox protein 1.2 (LMX-1.2); LIM/homeobox protein LMX1B; LMX1B_MOUSE; LIM homeobox transcription factor 1 beta; LIM homeobox transcription factor 1, beta
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human LMX1b/NPS1: 111-210/379
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
42 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
This gene encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
指甲髌骨综合征相关蛋白NPS1抗体-bs-11780R指甲髌骨综合征相关蛋白NPS1抗体-bs-11780R指甲髌骨综合征相关蛋白NPS1抗体-bs-11780R指甲髌骨综合征相关蛋白NPS1抗体-bs-11780R指甲髌骨综合征相关蛋白NPS1抗体-bs-11780R指甲髌骨综合征相关蛋白NPS1抗体-bs-11780R指甲髌骨综合征相关蛋白NPS1抗体-bs-11780R指甲髌骨综合征相关蛋白NPS1抗体-bs-11780R

产品应用

应用已检合格种属预测种属推荐稀释比例
IHC-PMouse, RatHuman, Pig, Sheep, Cow, Dog1:100-500
IHC-FMouse, RatHuman, Pig, Sheep, Cow, Dog1:100-500
IFMouse, RatHuman, Pig, Sheep, Cow, Dog1:100-500

交叉反应

交叉反应: Mouse, Rat (predicted: Human, Pig, Sheep, Cow, Dog)

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靶标

基因名
LMX1B
蛋白名
LIM homeobox transcription factor 1-beta
亚细胞定位
Nucleus.
组织特异性
Expressed in most tissues. Highest levels in testis, thyroid, duodenum, skeletal muscle, and pancreatic islets.
疾病
Defects in LMX1B are the cause of nail-patella syndrome (NPS) [MIM:161200]; also known as onychoosteodysplasia. NPS is a disease that cause abnormal skeletal patterning and renal dysplasia.
相似性
Contains 1 homeobox DNA-binding domain.
Contains 2 LIM zinc-binding domains.
功能
Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels.

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