A型流感病毒H5N1凝集素抗体

bs-2284R

H5N1 Hemagglutinin Rabbit pAb

A型流感病毒H5N1凝集素抗体

[Influenza A virus(A/chicken/West Bengal/100879/2008(H5N1))]; Influenza A virus Hemagglutinin[H5N1; H5N1 HA.; H5;

Rabbit

KLH conjugated synthetic peptide derived from Hemagglutinin/Influenza A virus (H5N1): 200-300/568

IgG

Liquid

affinity purified by Protein A

Polyclonal

64 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

2004年在我国发生的禽流感疫情,主要是由H5亚型引起的,其发病率和死亡率都很高,危害性大。H5亚型禽流感病毒,对鸡、火鸡和鸭均可感染发病,是人与动物共患的流感病原体。由于病毒多变异,导致A型禽流感反复发生,难以有效控制。

Influenza A virus is a major public health threat. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species jumping ability. Influenza A Virus Hemagglutinin antibodies recognize the influenza hemagglutinin epitope, which has been used extensively as a general epitope tag in expression vectors. The extreme specificity of this antibody allows for unambiguous identification and quantitative analysis of the tagged protein.