Myelin protein-zero is the major structural protein of peripheral myelin, accounting for more than 50% of the protein present in the sheath of peripheral nerves. Expression of the gene encoding Myelin protein-zero (MPZ) is restricted to Schwann cells; MPZ is not found in the CNS. An integral membrane glycoprotein of ~28kDa, Myelin protein-zero is thought to link adjacent lamellae and thereby stabilize the myelin assembly. The other 3 major components of myelin are myelin basic protein, myelin proteolipid protein and myelin-associated glycoprotein.
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
WB
Mouse, Rat
Human, Rabbit
1:500-2000
交叉反应
交叉反应: Mouse, Rat (predicted: Human, Rabbit)
相关产品
暂无相关产品
靶标
基因名
MPZ
蛋白名
Myelin protein P0
亚基
Homodimer and homotetramer.
亚细胞定位
Cell membrane; Single-pass type I membrane protein.
组织特异性
Found only in peripheral nervous system Schwann cells.
相似性
Belongs to the myelin P0 protein family. Contains 1 Ig-like V-type (immunoglobulin-like) domain.