肝脏X受体β抗体

bs-18450R

宠物抗体、农牧业/家禽抗体

LXR beta Rabbit pAb

肝脏X受体β抗体

LXR-b; LXRB; NER; NER-I; RIP15; UNR; LXR beta; LXRbeta; OR-1; NR1H2_HUMAN; NR1H2; Liver X receptor beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; Ubiquitously-expressed nuclear receptor; NR1H2_RAT; Orphan nuclear receptor OR-1; Ubiquitously-expressed nuclear receptor (UR);

Rabbit

KLH conjugated synthetic peptide derived from human LXR beta: 361-460/460

IgG

Liquid

affinity purified by Protein A

Polyclonal

51 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]